Figure 2:
Biglycan synthesis in ASMCs from ApoE
+/+
and ApoE
-/-
mice is not sensitive to imatinib.
ASMCs were treated with and imatinib (10 μM) in the presence of [
35
S]-SO
4
(50 μCi/ml) for 24 hr. Isolated proteoglycans were separated by SDS-PAGE.
