Vectors |
Genes |
Species/Cells |
Locations |
References |
Adenovirus |
Bmp-2 |
Rat |
Femur |
[68] |
Osteoporotic sheep |
Injury site |
[69] |
Goat |
Tibia |
[73,81] |
Bmp-7 |
Rat |
Alveolar bone defect |
[74] |
Rat |
Alveolar bone defect |
[76] |
Pdgf-bb |
Rat |
Alveolar bone defect |
[75] |
AAV |
Bmp-2 |
Mouse |
Cranial defect |
[83] |
Rat |
Hind limb |
[81] |
Bmp-4 |
Immunocompetent rat |
Intramuscular |
[80] |
Rankl/Vegf |
Mouse |
Femoral bone allograft |
[82] |
Retrovirus |
Bmp-2 |
SCID mouse/BMSCs |
Hind limb |
[171] |
Bmp-4 |
Mouse/MDSCs |
Subcutaneous back |
[86] |
Polyethylenimine |
Bmp-4 |
Rat |
Cranial defect |
[91] |
Polyethyleneglyco |
Runx2/caAlk6 |
Mouse |
Skull bone |
[92] |
Electroporation |
Bmp-2 |
Mouse |
Skeletal muscle |
[94] |
Bmp-4 |
Rat |
Gastrocnemius |
[95] |
Ultrasound |
Bmp-11 |
Canine |
Pulp tissue |
[96] |
Bone Marrow Stromal Cells (BMSCs); Bone Morphogenetic Protein 2 (BMP-2); constitutively active activin receptor-like kinase 6 (caALK6); Muscle-Derived Stem Cells
(MDSCs); Platelet Derived Growth Factor (PDGF); receptor activator for nuclear factor-κB ligand (RANKL); runt-related transcription factor 2 (Runx2); and Vascular
Endothelial Growth Factor (VEGF). |