| Number of participants (n) |
First Study (n=180) |
Second Study (n=186) |
| Males |
69 |
68 |
| Females |
111 |
117 |
| No gender provided |
|
1 |
| p-value (d) |
p=0.829 (b) |
| Age |
| Mean Age |
41.0 |
44.0 |
| Number of respondents |
176 |
183 |
| No age data provided |
4 |
3 |
| p-value (a) |
p=0.024 (c) |
| Number of Cold Sores per year |
| Mean |
4.7 |
3.9 |
| Median |
4.0 |
3.0 |
| Number of respondents |
176 |
184 |
| p-value (a) |
p=0.011 (c) |
|
| Time to Healing – Loss of hard scab –Duration of Untreated Cold Sores |
First Study |
Second Study |
| Mean |
11.5 days |
11.3 days |
| Median |
11.0 days |
10.0 days |
| Number of respondents |
175 |
180 |
| p-Value (a) |
p=0.500 (b) |
| Viroxyn Time to Healing |
| Mean |
4.0 days |
3.5 days |
| Median |
3.0 days |
3.0 days |
| Number of respondents |
180 |
184 |
| p-value (a) |
p=0.054 (c) |
| Abreva Time to Healing |
| Mean |
7.6 |
7.6 |
| Median |
7.0 |
7.0 |
| Number of Respondents |
178 |
184 |
| p-value (a) |
p=0.910 (b) |
| Untreated time to loss of discomfort |
| Mean |
6.7 days |
6.6 days |
| Median |
6.0 days |
7.0 days |
| Number of respondents |
171 |
179 |
| p-value (a) |
p=0.807 (b) |
| Viroxyn Time to loss of discomfort |
| Mean |
0.6 days |
0.5 days |
| Median |
0.042 days |
0.0069 days |
| Number of respondents |
180 |
183 |
| p-value (a) |
p=0.235 (b) |
| Abreva Time to loss of discomfort |
|
| Mean |
2.8 |
2.8 |
| Median |
3.0 |
3.0 |
| Number of respondents |
177 |
182 |
| p-value (a) |
p=0.950 (b) |
| p-value Viroxyn vs. Control (a) |
p<0.001 (c) |
| p-value Abreva vs. Control I(a) |
p<0.001 (c) |
| p-value Viroxyn vs. Abreva (a) |
p<0.001 (c) |
a. Two tailed independent T-test