Figure 3: Shows the integrity of the collagen fleece and the results of the histomorphometrical thickness measurements. A1-A4 Show the fleece´s profile (CFM=double arrows) during the observation period (H & E-stainings, 200x magnification, scale bars = 100 μm). Note that at day 60 a fragmentation of the fleece was observed, so that no histological results of this study time point were incorporated. B) Shows the results of the histomorphometrical analysis of fleece´s thickness from day 3 until day 30 after implantation (* = statistical significance).