Figure 6: Action of pSS IgG anti M3 on semi-quantitative RT-PCR analysis for iNOS (A), nNOS (B) and eNOS (C) mRNA levels from submandibular gland incubated during one hour with 1x10-8 M pSS IgG anti M3 in absence or in presence of 1x10-4 M synthetic M3 peptide and 1x10-5 M S-Methyl-U (A) or 1x10-4 M synthetic M3 peptide and 5x10-6 M L-NIO (B) or 1x10-4 M synthetic M3 peptide and 5x10-6 M N-PL (C). Basal value corresponds to mRNA level after one hour incubation without antibodies or drug inhibitors. Normal IgG anti M3 (1x10-8 M) are also shown. The RT-PCR products obtained were: *P<0.0001 versus nIgG anti M3 and basal and **P<0.001 versus pSS IgG anti M3. The internal control for the mRNA of the housekeeping gene of glyceraldehyde-3-phosphate-dehydrogenase (g3pdh) is shown.