|
|
ARIC (n=12,771) |
FOS (n=2,760) |
MESA (n=5,652) |
P-value |
Sex |
|
|
|
|
Male (n, %) |
5704 (44.7%) |
1258 (45.6%) |
2753 (48.7%) |
<0.0001 |
Age (mean±SD, in years) |
54.1± 5.7 |
33.7±9.3 |
62.4±10.3 |
<0.0001 |
Ethnicity |
|
|
|
<0.0001 |
White |
9633 (75.4%) |
2696 (97.7%) |
2224 (39.4) |
|
Black |
3138 (24.6%) |
7 (0.3%) |
1386 (24.5%) |
|
Other |
- |
57 (2%) |
2042 (36.1%) |
|
HDL (mg/dl) |
51.5±16.9 |
51.5±14.5 |
50.8±14.8 |
0.009 |
LDL (mg/dl) |
137.9±39.2 |
120.1±32.9 |
117.2±31.6 |
<0.0001 |
SBP (mm Hg) |
120.9±18.5 |
119.0±14.2 |
134.4±19.0 |
<0.0001 |
DBP (mm Hg) |
73.6±11.2 |
77.1±9.9 |
75.2 ±10.0 |
<0.0001 |
BMI (kg/m2) |
27.7±5.3 |
24.9±4.1 |
28.3±5.5 |
<0.0001 |
Current smoker (n, %) |
3291 (25.8%) |
1065 (38.7%) |
708 (12.5%) |
<0.0001 |
Follow-up time (in years) |
|
|
|
|
Mean±SD |
15.4±2.9 |
31.0±4.0 |
6.1±1.2 |
<0.0001 |
Median |
16.1 |
32.3 |
6.5 |
<0.0001 |
Baseline T2D prevalence (n, %) |
1484 (11.6%) |
13 (0.5%) |
717 (12.7%) |
<0.0001 |
T2D incidence (n, %) |
1249 (9.8%) |
272 (9.9%) |
400 (7.1%) |
<0.0001 |
GRS |
13.3±4.2 |
11.7±2.8 |
14.2±3.9 |
<0.0001 |
Abbreviations: HDL: High Density Lipoprotein; LDL: Low-Density Lipoprotein; SBP: Systolic Blood Pressure; DBP: Diastolic Blood Pressure; BMI: Body Mass Index; T2D: Type 2 Diabetes; GRS: Genotype Risk Score |
|