| |
Staphylococcus aureus N (%) |
Streptococcus pneumoniae N (%) |
p value |
| N |
42 |
93 |
|
| Mean age ± SD, years |
46 ± 9 |
44 ± 8 |
0.27 |
| Male |
|
32 (76) |
68 (73) |
0.71 |
| Race |
White/Caucasian |
22 (52) |
31 (33) |
0.04 |
| |
Black/African American |
19 (45) |
54 (58) |
0.17 |
| |
Other |
1 (2) |
8 (9) |
0.27 |
| Homeless |
9 (21) |
23 (25) |
0.68 |
| Current alcohol abuse (missing 1) |
13 (31) |
34 (37) |
0.50 |
| Current IDU (missing 1) |
7 (17) |
26 (28) |
0.15 |
| Current tobacco use (missing 1) |
21 (50) |
74 (80) |
<0.001 |
| Median CD4µL cell count (IQR), cells per |
185 (76–386) |
239 (94–442) |
0.27 |
| Geometric mean HIV viral load (95%CI),
copies per mL |
4750 (1658–
13,610) |
12,238 (6834–
21,913) |
0.09 |
| Median WBC count (IQR), cells x 103/mm3 |
9.3 (5.7–13.3) |
10.7 (7.7–16.6) |
0.09 |
| Mean O2 saturation§±SD |
91 ± 6 |
92 ± 5 |
0.46 |
| Prior pneumococcal vaccination (missing 3) |
7 (18) |
21 (23) |
0.49 |
| PCP prophylaxis |
23 (55) |
20 (22) |
<0.001 |
| TMP-SMX to prevent PCP |
14 (33) |
14 (15) |
0.02 |
| Chronic lung disease |
20 (48) |
28 (30) |
0.05 |
| Other co-morbid diagnosis* |
37 (88) |
60 (65) |
0.004 |
Note: IDU=intravenous drug use; PCP = Pneumocystis jirovecii pneumonia; WBC = White Blood Cell; TMP-SMX= Trimethoprim-Sulfamethoxazole; SD= Standard
Deviation, IQR= Inter-Quartile Range, CI= Confidence Interval
§O2 saturation indicates percent hemoglobin oxygen saturation breathing ambient air
* Co-morbid diagnoses include any one or combination of the following: hepatitis without cirrhosis (n=77), hepatitis with cirrhosis (n=8), anemia (n=10), chronic renal
insufficiency (n=5), diabetes mellitus (n=4), cancer (n=4), congestive heart failure (n=3), coronary artery disease (n=2), Immune Thrombocytopenic Purpura (ITP) (n=2),
Thrombotic Thrombocytopenic Purpura (TTP) (n=1), Kaposi’s malignancy (n=2), pancytopenia (n=1), protein C&S deficiency (n=1), history of splenectomy (n=1), stroke
(n=1) |