gene miRNA/5'region 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 bcd dme-miR-79 T A A A G C T A G A T T A C C A A A G C A T       hb 5'(-4333)F C A A A G C T T T G C C C A A A T T A A G T         coincidence   ο ο ο ο ο ο                 ο           ο         5'(-3078)F A A A A G C T T T C C G C G G A T A A A C A         coincidence   ο ο ο ο ο ο                 ο   ο                 5'(-4326)R C A A A G C T T T G C C A C A A T T A G C A         coincidence   ο ο ο ο ο ο           ο ο   ο                     5'(-3071)R G A A A G C T T T T G C G A A T T T C T A C         coincidence   ο ο ο ο ο ο                                     bcd dme-miR-4 A T A A A G C T A G A C A A C C A T T G A         hb 5'(-4284)F T T A A A G C A A C A A G G A A T C T C C           coincidence   ο ο ο ο ο ο   ο   ο               ο             bcd dme-miR-286 T G A C T A G A C C G A A C A C T C G T G C T     hb 5'(-1576)F C G A C T A G C A C A T G T T T A G T T T A C       coincidence   ο ο ο ο ο ο     ο                   ο           bcd dme-miR-279 T G A C T A G A T C C A C A C T C A T T A A       hb 5'(-1576)F C G A C T A G C A C A T G T T T A G T T T A         coincidence   ο ο ο ο ο ο     ο           ο     ο ο   ο       bcd dme-miR-996 T G A C T A G A T T T C A T G C T C G T C T       hb 5'(-1576)F C G A C T A G C A C A T G T T T A G T T T A         coincidence   ο ο ο ο ο ο             ο           ο           bcd dme-miR-999 T G T T A A C T G T A A G A C T G T G T G T C T   hb 5'(-4308)R T G T T A A C T T A A T T T G G G C A A A G C T     coincidence ο ο ο ο ο ο ο ο     ο           ο           ο ο   bcd dme-miR-315 T T T T G A T T G T T G C T C A G A A A G C       hb 5'(-961)R C T T T G A T T T G C G T A G T T T T T C T         coincidence   ο ο ο ο ο ο ο       ο                           hb 5'(-3557)R T T T T G A T A G C A G T T A C G T T T C G         coincidence ο ο ο ο ο ο ο   ο     ο   ο     ο                 bcd dme-miR-1000 A T A T T G T C C T G T C A C A G C A G T         hb 5'(-4657)F G T A T T G T A T A G A G A A A A A A G G           coincidence   ο ο ο ο ο ο       ο     ο   ο     ο ο           hb 5'(-1192)F G T A T T G T A G A T A T T T T A G C T G           coincidence   ο ο ο ο ο ο                                     hb 5'(-296)F A T A T T G T T A G C C A T T A C C A A G           coincidence ο ο ο ο ο ο ο                 ο   ο ο             hb 5'(-2533)R A T A T T G T T T T A G A A T T T T T G C           coincidence ο ο ο ο ο ο ο     ο       ο           ο           5’(-xxxx)F/R: xxxx-start position in 5’ upstream, F-Forward strand, R-Reverse strand

bcd dme-miR-283 T A A A T A T C A G C T G G T A A T T C T     hb 5'(-4897)F T A A A T A T T G C T T T T A C A T T T T       coincidence ο ο ο ο ο ο ο         ο         ο ο ο   ο     hb 5'(-4820)F A A A A T A T T C G A C A T A A A C A G G       coincidence   ο ο ο ο ο ο     ο           ο ο             hb 5'(-4788)F C A A A T A T T C C A C A T A A A C A G G       coincidence   ο ο ο ο ο ο                 ο ο             hb 5'(-3555)F C A A A T A T T G C A T T A A A T A C A A       coincidence   ο ο ο ο ο ο         ο       ο               hb 5'(-2134)F C A A A T A T A A T G A A T A C A C C T A       coincidence   ο ο ο ο ο ο   ο               ο             hb 5'(-1948)F T A A A T A T G C A C A T A T A T A C G G       coincidence ο ο ο ο ο ο ο       ο       ο ο               hb 5'(-1283)F A A A A T A T C C A C A A A A G C G A A T       coincidence   ο ο ο ο ο ο ο     ο                   ο     hb 5'(-1258)F T A A A T A T G C T A A G C T T C A T T T       coincidence ο ο ο ο ο ο ο           ο   ο       ο   ο     hb 5'(-1019)F A A A A T A T A G G C A A C A A G C A A T       coincidence   ο ο ο ο ο ο     ο ο         ο         ο     hb 5'(-2531)R A A A A T A T T G T T T T A G A A T T T T       coincidence   ο ο ο ο ο ο         ο       ο ο ο ο   ο     hb 5'(-1917)R T A A A T A T A T C C C G T A T A A T A T       coincidence ο ο ο ο ο ο ο       ο   ο       ο   ο   ο     hb 5'(-1767)R A A A A T A T A T G T A T G T A T G C G T       coincidence   ο ο ο ο ο ο     ο       ο ο ο         ο     hb 5'(-1630)R A A A A T A T C A T G A A A A T G G C A A       coincidence   ο ο ο ο ο ο ο ο                             hb 5'(-1179)R A A A A T A T C T A C A A T A C T T A G G       coincidence   ο ο ο ο ο ο ο     ο             ο           hb 5'(-1092)R T A A A T A T T A T T A A T T T C G C A A       coincidence ο ο ο ο ο ο ο   ο           ο                 bcd dme-miR-989 T G T G A T G T G A C G T A G T G G A A C     hb 5'(-2869)F T G T G A T A T A C T T T C A A A A G A A       coincidence ο ο ο ο ο ο   ο         ο             ο       bcd dme-miR-1017 G A A A G C T C T A C C C A A A C T C A T C C hb 5'(-4333)F C A A A G C T T T G C C C A A A T T A A G T T   coincidence   ο ο ο ο ο ο   ο   ο ο ο ο ο ο   ο   ο       hb 5'(-3078)F A A A A G C T T T C C G C G G A T A A A C A A   coincidence   ο ο ο ο ο ο   ο   ο   ο     ο       ο       hb 5'(-4326)R C A A A G C T T T G C C A C A A T T A G C A T   coincidence   ο ο ο ο ο ο   ο   ο ο     ο ο   ο           hb 5'(-3070)R G A A A G C T T T T G C G C A A T T T C T A C   coincidence ο ο ο ο ο ο ο   ο     ο     ο ο   ο     ο   ο bcd dme-miR-79 T A A A G C T A G A T T A C C A A A G C A T   hb 5'(-4333)F C A A A G C T T T G C C C A A A T T A A G T     coincidence   ο ο ο ο ο ο                 ο           ο   hb 5'(-3078)F A A A A G C T T T C C G C G G A T A A A C A     coincidence   ο ο ο ο ο ο                 ο   ο           hb 5'(-4326)R C A A A G C T T T G C C A C A A T T A G C A     coincidence   ο ο ο ο ο ο           ο ο   ο               hb 5'(-3070)R G A A A G C T T T T G C G C A A T T T C T A     coincidence   ο ο ο ο ο ο             ο   ο       ο ο

Table 2a: Relations between the miRNAs of bcd and the 5’ upstream region of h.