| Sindhi Sub groups |
β-Thalassaemia |
HbD |
HbQ |
| N |
No.of
β-thal trait (%) |
N |
No.
HbD trait (%) |
No. HbD
homozygote |
No.
HbD-β thal
(%) |
N |
No.
HbQ trait (%) |
No.
HbQ-β thal
(%) |
| Sahiti |
227 |
21(9.25) |
227 |
6 (2.64) |
- |
- |
227 |
1 (0.44) |
- |
| Ghotki |
261 |
47(18.01) |
261 |
10 (3.83) |
- |
1 (0.79) |
261 |
- |
- |
| Ladkana |
477 |
72(15.09) |
477 |
7 (0.79) |
- |
1 (0.79) |
477 |
5 (1.05) |
1 (0.21) |
| Sakhru |
127 |
26(20.47) |
127 |
1 (0.79) |
- |
1 (0.79) |
127 |
- |
- |
| Mixed Others* |
180 |
25(13.89) |
180 |
2 (1.11) |
- |
- |
180 |
- |
- |
| Unspecified |
226 |
26(11.50) |
226 |
2 (0.88) |
- |
- |
226 |
- |
- |
| Total |
1498 |
217(14.49) |
1498 |
28 (1.87) |
- |
3 (0.20) |
1498 |
6 (0.40) |
1 (0.07) |
N= number tested
*1 case of HPFH heterozygote in Chhapru Sindhis
χ2 test of homogeneity: β-thal 12.85 (df 5), p < 0.05 significant
HbD 40.91 (df 15), p < 0.001 significant
HbQ 9.84 (df 10), p > 0.05 insignificant |
