| Ca-Se
(Fami-Ly) |
Twins |
Breast Cancer in
Sister |
Age |
10 Slavic Mutations ofGenes BRCA1/2 |
Mutations Of Genes BRCA1/2Diagnosed in Another Country |
Breast
Cancer
in
Another
Relatives |
Age |
Mother/
Father
Line |
Other
Oncology
Pathology |
Mother’s
Line |
Father’s
Line |
| 1.K |
DZ |
younger |
45 |
negative |
- |
mother |
42 |
mother |
visceral cancer |
Grand mother |
- |
| 2.F |
DZ |
younger |
42 |
negative |
- |
mother,
aunt |
39
43 |
mother’s
line |
pharyngeal
cancer |
uncle |
- |
| 3.V |
MZ |
both |
40/41 |
negative in younger sister |
BRCA2 c.6405_6409delCTTAA (p.Asn2135fs) in elder sister |
cousin,
grandmother |
30
60 |
father’s
line
mother’s
line |
gastric,
pancreas |
- |
grandmother
grandfather |
| 4.L |
DZ |
both |
37/43 |
negative in both sisters |
- |
- |
|
- |
cancer uterus
visceral cancer |
mother
grandfather |
- |
| 5.S |
DZ |
both |
47/48 |
negative in younger sister |
BRCA1 5382InsC in elder sister |
grandmother |
55 |
mother’s
line |
- |
- |
- |
