Low Melanoma Incidence Area/Population
• An individual with two primary melanomas
• Two cases of melanoma among first or second degree relatives on the same side of the family
• One case of melanoma and one case of pancreatic cancer in first or second degree relatives on the same side of the family
Moderate/High Melanoma Incidence Area/Population
• An individual with three primary melanomas
• Three cases of melanoma among first or second degree relatives on the same side of the family
• One case of melanoma and two cases of melanoma and/or pancreatic cancer among first or second degree relatives on the same side of the family
Table 2: Criteria for considering CDKN2A/p16 gene testing [27].