PARAMETER SCORE
Population is clearly defined  1/0
Inclusion criteria are clearly stated   1/0
Exclusion criteria are clearly stated   1/0
PE vs CTR matched or P>.05 for maternal characteristics: BMI (1/0), age (1/0), weight (1/0), smoking (1/0), ethnicity (1/0) 1/2/3/4/5/0
PE vs CTR matched or P>.05 gestational age   1/0
PE vs CTR matched or P>.05 birth weight   1/0
Statistical methods appropriate   1/0
Statement of diagnostic criteria for PE (exposure)   1/0
Measurement of epigenetic change conducted (outcome)   1/0
Were results adjusted and controlled for confounders?   1/0
Limitations of experimental study identified   1/0
Total max score  15
PE-Preeclampsia; CTR-Control; BMI: Body Mass Index
Table 1: Quality assessment parameters and scores.