| Study |
Number of PE and CTR Placentas Studied |
miRNA studied |
DNA methylation studied |
Gestational age at delivery(in weeks) |
Gestational age at delivery(in weeks) |
| Total |
PE |
CTR |
Mild PE |
Severe PE |
EOPET |
LOPET |
Early CTR |
PE |
Control |
| Bai [35] |
32 |
15 |
17 |
|
|
|
|
|
miR-195 |
|
37.42 ± 2.57 |
38.86 ± 1.2 |
| Czikk [26] |
59 |
18 |
|
|
|
|
|
14 |
|
DUSP9 |
30.1 ± 2.2 |
32.3 ± 2.2 |
| Gao [36] |
48 |
|
24 |
|
|
10 |
14 |
|
|
|
27.9 ± 3.3 EOPET 27.9 ± 3.3 LOPET |
28.6 ± 2.5 |
| Hu [24] |
50 |
|
26 |
|
24 |
|
|
|
miR-16, miR-29b, miR-195, miR-26b, miR-181a, miR-335 and miR-222 |
|
37 ± 0.2 |
38.8 ± 0.4 |
| Li [23] |
50 |
24 |
26 |
|
|
|
|
|
miR29-b |
|
37 |
38.8 |
| Muralimanoharan [25] |
12 |
6 |
6 |
|
|
|
|
|
miR-210 |
|
38.1 ± 1.3 |
38.7 ± 1.1 |
| Xiang [37] |
79 |
48 |
31 |
|
|
|
|
|
|
CGI34, LEP, SP1, LP1, CEBPalpha |
35.34 ± 3.07 |
39.38 ± 1.19 |
| Yan [38] |
24 |
12 |
12 |
|
|
|
|
|
mir-126 |
|
35.54 ± 3.77 |
37.5 ± 1.76 |
| Yuen [39] |
22 |
|
5 |
|
|
4 |
4 |
4 early 5 late |
|
CAPG, GLI2, KRT1, TIMP3 |
24.86-34 |
25.86-33.71 |
| Zhu [22] |
34 |
|
11 |
8 |
15 |
|
|
|
miR-518b, miR-18a, miR-363, miR-542-3p, miR-210, miR-152, miR-411, miR-377 |
|
37.6 ± 1.4 |
37.5 ± 2.2 |
PE: Preeclampsia; CTR: Control; EOPET: Early Onset Preeclampsia; LOPET: Late Onset Preeclampsia |
