| Study |
miRNA investigated |
miRNA |
p-value |
Target gene |
| Upregulated |
Downregulated |
| Bai [35] |
miR-195 |
|
✔ |
<0.05 |
ActRIIA |
| Gao [36] |
miR-675 |
|
✔ (EOPET) |
<0.05 |
NOMO1 |
| Hu [24] |
miR-16, miR-29b, miR-195, miR-26b, miR-181a, miR-335 and miR-222 |
✔ (severe PE) |
|
<0.05 |
|
| Li [23] |
miR29-b |
✔ |
|
<0.001 |
MCL1, MMP2, VEGF, ITGB1 |
| Muralimanoharan [25] |
miR-210 |
✔ (severe PE) |
|
<0.05 |
ISCU |
| Zhu [22] |
miR-210 |
✔ (severe PE) |
✔ (mild PE) |
<0.05 |
|
| Zhu [22] |
miR-152 |
✔ (mild and severe) |
|
<0.05 |
|
| Zhu [22] |
miR-518b |
✔ (severe PE) |
|
<0.05 |
|
| Zhu [22] |
miR-18a, miR-363, miR-542-3p |
|
✔ (severe PE) |
<0.05 |
|
| Zhu [22] |
miR-411, miR-377 |
|
✔ (mild and severe PE) |
<0.05 |
|
| Yan [38] |
mir-126 |
|
✔ |
<0.05 |
PIK3R2 gene |
PE: Preeclampsia; EOPET: Early Onset Preeclampsia |
