Glutathione (mmol/g Hb) Catalase (k/g Hb)
baseline value after painful stimulation baseline value after painful stimulation
Group C 3.32±0.47 3.29 ±0.41 418.43±51.24 406.38±44.23
Group ISO 3.25±0.56 3.34±0.36 420.32±63.91 412.44 ±58.82
Group N 3.29±0.34 4.71±0.44 ▲ 416.74±48.63 589.38±54.83★
Group L 3.43±0.38 3.82±0.42■ 420.26±87.18 492.42 ±39.45•
Group L+N 3.33±0.45 5.52±0.24◆ 421.34±75.96 687.36 ±62.75✯
Data are means ± SD
▲After painful stimulation, in Group N, compared to Group C (p=0.0022), Group ISO (p=0.0028) and Group L (p=0.032) for glutathione levels.
■After painful stimulation, in Group L+N, compared to Group C (p<0.0001), Group ISO (p<0.0001), Group L (p<0.0001) and Group N (p=0.041) in for glutathione
levels.
◆After painful stimulation, in Group L, compared to Group C (p=0.043), Group ISO (p=0.042), for glutathione levels.
★After painful stimulation, in Group N, compared to Group C (p=0.0024), Group ISO (p=0.0019) and Group L (p=0.028) for catalase levels.
•After painful stimulation, in Group L+N, compared to Group C (p<0.0001), Group ISO (p<0.0001) and Group L (p=0.005) for catalase levels.
✯After painful stimulation, in Group L, compared to Group C (p=0.024) and Group ISO (p=0.022) for catalase levels.
Table 3: Changes in glutathione and catalase levels before drugs administration and after painful stimulation.