Parameter Control Lidocaine Diltiazem Esmolol p-value
SBP (mmHg) 131.6 ± 1.59 131.2 ± 1.79 128.2 ± 1.45 126.3 ± 1.37 0.0478
DBP (mmHg) 87.10 ± 0.87 86.00 ± 0.88 83.50 ± 0.73* 79.03 ± 0.93*** P<0.0001
HR (per min) 98.13 ± 1.47 97.80 ± 1.40 87.70 ± 1.41** 88.20 ± 1.39*** P<0.0001
MAP (mmHg) 101.9 ± 0.75 101.1 ± 0.76 98.38 ± 0.73** 94.77 ± 0.77*** P<0.0001
RPP 12910 ± 248.8 12840 ± 261.7 11270 ± 257.9 *** 11140 ± 221.5*** P<0.0001
Data are presented as means ± SEM, and p value. ANOVA with repeated measures was used to compare the changes in SBP, DBP, HR, MAP and RPP values. p is significant at <0.05*, <0.01** and <0.001***
Table 5: Change in haemodynamic variables in the study groups at 5 min.