| 
      
        | Duration    of Observation | Substance-P Level    (pg/ml) | P    value |  
        | Pregabalin Group    (n=26) | Control Group (n=26) |  
        | Min–Max | Median | Min-Max | Median |  
        | Before    Surgery | 11-185 | 48.5 | 6-154 | 60.5 | p=0.510 |  
        | 1hr  After Surgery | 2.3-173.5 | 19.3 | 23.6-205.6 | 59.6 | p=0.000* |  | 
  
    | Data are shown in minimal, maximal and mean value, deviation standard
      and probability were tested with Mann Whitney-U test, p<0.05 is significant. *P
    value<0.05. | 
  
    | Table 3: Substance-P level alteration between two groups. |