Historic Controls
n=68
Study Group
n=104
p-value
Hemoglobin at discharge (mg/dL) 10.7(10-12.2) 10.8(9.6-11.8) 0.23
Platelets at 4th postoperative day (x 109/L) 128(97-176) 146(106-208) 0.08
Ratio Prothrombin Time at 4th postoperative day 1.30(1.17-1.46) 1.23(1.14-1.34) 0.09
AST/ALT at 4th postoperative day (U/L) 305(158-523) 247(159-432) 0.35
Bilirubin at 4th postoperative day (mg/dL) 1.5(1-2.8) 1.2(0.8-1.9) 0.01
Complication rate stratified by Clavien
No complications
I
II
III
IV
V
38(56%)
4(6%)
15(22%)
6(9%)
4(6%)
1(2%)
68(65%)
6(6%)
22(21%)
4(4%)
3(3%)
1(1%)
0.66
Re-intervention n (%) 6(9) 3(3) 0.01
Re-intervention for bleeding n (%) 1(1,5) 0 0.39
Intensive Care Unit Stay (days) 1(0-3) 1(0-3) 0.49
In hospital Stay (days)
Overall
Laparoscopic approach
Open surgery
10(7-14)
6 (5-13)
10 (8-15)
7(5-11)
4 (3-7)
9 (6-14)
<0.01
0.07
0.02
Definition of Abbreviations: p value = statistical significance comparing both groups. Data expressed as median (25-75%)
Table 3: Comparison of postoperative complications and outcome data between historic controls (2009) and study group (January 2012-June 2013).