Parameters Control (n=30) Lidocaine (n=30) P-value
SBP 2 min before extubation 113 ± 7.67
114(95-126)
111 ± 6.73
110(101-130)
0.14
SBP 2 min after extubation 130 ± 4.87°
130(119-139)
120.96 ± 1.56°
121(117-124)
0.0001*
SBP 5 min after extubation 114.96 ± 5.22
116(103-125)
113.96 ± 6.59
113(100-127)
0.50
SBP 10 min after extubation 112 ± 6.54
112(102-126)
112.03 ± 3.25
112(103-118)
0.85
DBP 2 min before extubation 69.03 ± 5.11
69(61-80)
66.93 ± 4.07
67(56-75)
0.16
DBP 2 min after extubation 75.10 ± 5.19°
74(68-86)
71 ± 3.18°
71(65-76)
0.002*
DBP 5 min after extubation 70.03 ± 4.29
70.5(60-81)
67.83 ± 1.01
68(66-70)
0.003*
DBP 10 min after extubation 67.96 ± 5.24
67.5(54-81)
66.03 ± 2.55
66(61-72)
0.09
HR 2 min before extubation 80.03 ± 10.78
80.5(62-104)
78.03 ± 14.29
79(45-107)
0.56
HR 2 min after extubation 85.96 ± 12.74
86(62-104)
82.06 ± 12.10
79.5(64-115)
0.15
HR 5 min after extubation 81.10 ± 9.88
79.5(53-102)
78.96 ± 2.04
79(74-83)
0.49
HR 10 min after extubation 81.93 ± 10.20
82(62-108)
78 ± 3.22
77(73-84)
0.12
Data are expressed as mean ± standard deviation and median (range); °Significant difference with baseline (within group); * Significant difference between groups; Mann-Whitney test was used for intergroups comparisons and Wilcoxon test was for within group comparison. SBP: Systolic blood pressure; DBP: Diastolic blood pressure; HR: Heart rate.
Table 2: Comparison of hemodynamic changes before and after tracheal extubation in the studied groups.