UNGROUPED Control HDMA Ozone HDMA/Ozone Eosinophils Epithelium -0.01 0 -0.205 -0.33 -0.17 Eosinophils Interstitium -0.05 0.18 -0.3 -0.57 0.03 Vessel Density 0.07 0.67 0.530 -0.48 0.420

Table 2a: Correlation with epithelial VEGF-proximal airways.