Cough group SOB group Cough with SOB group Control  
IL4RA175V IL-9 IL4RA175V IL-9 IL4RA175V IL-9 IL4RA175V IL-9  
G/G (n=3) 29±3 G/G (n=0)   G/G (n=3) 88±58 G/G (n=8) 18±4.7 P=0.009*
A/G (n=12) 25 ± 11 A/G (n=18) 35±17 A/G (n=20) 39±29 A/G (n=7) 34±14 P=0.1
A/A (n=5) 28±17 A/A (n=12) 29±11 A/A (n=9) 85 ± 65 A/A (n=5) 42± 15 P=0.05*
  P=0.8   P=0.7   P=0.3   P=0.4  
IL4C-590T IL-17 IL4C-590T IL-17 IL4C-590T IL-17 IL4C-590T IL-17  
C/C (n=3) 267 ± 109 C/C (n=3) 263 ± 240 C/C (n=3) 65 ± 50 C/C (n=4) 79 ± 7.1 P=0.2
C/T (n=15) 120 ± 88 C/T (n=17) 108 ± 72 C/T (n=24) 154 ± 146 C/T (n=14) 88 ± 15 P=0.3
T/T (n=2) 57 ± 28 T/T (n=10) 129 ± 73 T/T (n=5) 137 ± 65 T/T (n=2) 103 ± 38 P=0.5
  P=0.06
P∏=0.04*
  P=0.5   P=0.3   P=0.5  
Results are expressed as mean ± Standard deviation.P value based on one way ANOVA, and independent sample T test *Statistical significance was defined as P ≤ 0.05. PΠ for difference between CC, CT is significant (0.04*)
Table 4: Serum levels of IL-9 and IL-17 cytokines (pg/ml) in individuals with different genotypes of the IL-4RA 175V and IL-4C-590T genes in the three asthmatic phenotypes.