SNP loci Genotype, No. (%) Allele Allele HWE
Intron 2 A>T AA AT TT Frequency Frequency P-value
Exon 4 T>C TT TC CC   P-value  
Intron 2 A>T T allele
AERD 49 40 14 0.333 0.099 0.009 0.216
-47.60% -38.80% -13.60%
ATA 162 114 24 0.27 - 0.123 0.553
-54.00% -38.00% -8.00%
NC 63 31 6 0.215 0.123 - 0.414
-63.00% -31.00% -6.00%
Exon 4 T>C C allele
AERD 55 41 7 0.281 0.01 0.009 0.863
-53.40% -39.80% -6.80%
ATA 200 90 10 0.183 - 0.455 0.974
-66.70% -30.00% -3.30%
NC 72 24 4 0.16 0.455 - 0.284
-72.00% -24.00% -4.00%
Table 2: Genotype and allele frequencies of the intron 2 A>T and exon 4 T>C gene in each group.