| SNPs loci |
FEV1 |
Total IgE |
Eosinopil |
| Genotype |
(% predicted) |
(IU/mL) |
(cells/μL) |
| Intron 2 A>T |
| |
AA |
74.1 ± 11.9 |
214.9 ± 208.8 |
698.1 ± 957.2. |
| |
AT/TT |
73.7 ± 11.2 |
144.9 ± 130.7 |
672.2 ± 585.9 |
| P-value |
0.875 |
0.141 |
0.877 |
| Exon 4 T>C |
| |
TT |
76.1 ± 11.3 |
165.7 ± 155.0 |
604.9 ± 783.7 |
| |
TC/CC |
71.4 ± 11.0 |
234.3 ± 290.7 |
777.2 ± 803.3 |
| |
P-value |
0.039 |
0.19 |
0.301 |
|
| aDifferences in the mean value of the phenotypic characteristics
within the patients were compared by t-test. Values in bold indicate
significant P-Value. FEV1: Forced Expiratory Volume in One Second;
IgE: Immunoglobulin E. |
| Table 4: Comparison of the clinical characteristics according to intron
2 A>T and exon 4 T>C gene polymorphisms in Japanese patients with
aspirin-exacerbated respiratory diseasea. |
