Concentration

Mean ± SD (μg/mL)

CV (%)

% diff

 

TMP

SMX

TMP

SMX

TMP

SMX

Low

0.4240 ± 0.0219

2.1572 ± 0.1002

5.23

4.71

Min = -0.92%

Min = -0.02%

 

 

 

 

 

Max = 12.09%

Max = 13.62%

Mid

0.6444 ± 0.0269

3.3959 ± 0.1645

4.15

4.87

Min = 0.10%

Min = 0.02%

 

 

 

 

 

Max = -11.74%

Max = 13.22%

High

0.9884 ± 0.0358

5.1658 ± 0.1981

3.65

3.90

Min = 0.50%

Min = -0.02%

 

 

 

 

 

Max = -14.60%

Max = 13.63%

Table 1: Accuracy and precision from the determination of cotrimoxazole in human plasma (n = 25/concentration).