Parameters

Test (mean±S.D.)

Reference (mean±S.D.)

Cmax (ng ml-1)

1052.47±254.41

1039.10±301.54

AUC(0-t) (ng h ml-1)

8737.48±1545.24

8850.04±1892.63

AUC(0-∞) (ng h ml-1)

9622.12±1692.57

9695.02±2133.95

tmax (h)

3.04±0.93

3.07±1.39

Kel (h-1)

0.10±0.06

0.10±0.03

(h)

7.44±1.85

7.24±2.10

Table 1: Mean pharmacokinetic parameters of the test and the reference formulations, each containing 100 mg troxipide.

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