Time (hr)

Subject M240

0

0

0.25

18.6

0.5

45.4

1

371.4

2

693.4

3

866

4

793.8

5

752.4

6

714.4

8

731.8

12

455.4

24

2903.6

36

1341

48

1063.6

Table 4: Data Set 4 Plasma concentrations (ng/ml) for AstraZeneca Compound B; dose = 20mg/kg in 100ml of solution.