(A) Enalapril Test Reference Parameter (unit) Mean Range Mean Range Cmax (ng/ml) 80.43 29.49 – 177.68 73.86 37.55 – 140.32 AUC0®last(ng.hr/ml) 129.71 58.82 – 302.67 122.10 70.50 – 205.92 AUC0®Inf(ng.hr/ml) 134.15 64.39 – 307.29 126.88 74.25 – 209.15 Parameter (unit) Median Range Median Range Tmax (hours) 1.00 0.75 – 3.67 0.75 0.50 – 2.33 T1/2 (hours) 1.08 0.62 – 1.75 1.24 0.75 – 2.36       (B) Enalaprilat Test Reference Parameter (unit) Mean Range Mean Range Cmax (ng/ml) 43.25 19.40 – 73.01 44.18 21.95 – 61.93 AUC0®last(ng.hr/ml) 399.41 210.45 – 646.50 390.93 217.20 – 626.51 AUC0®Inf(ng.hr/ml) 430.04 229.71 – 678.64 420.12 239.45 – 697.34 Parameter (unit) Median Range Median Range Tmax (hours) 4.00 2.67 – 6.00 4.33 2.33 – 6.00 T1/2 (hours) 14.00 4.73 – 33.60 12.28 4.94 – 28.76

Table 1: Pharmacokinetic parameters of enalapril and its active metabolite enalaprilat after a single oral dose of 20mg enalapril tablets under fasting conditions (n=26).