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Figure 1: Mean plasma concentration-time curves of telmisartan after the administration of a single dose of telmisartan (40 or 80 mg). Solid symbols represent the reference/test pair of formulations containing telmisartan 80 mg (n = 30). Open symbols represent the reference/test pair of formulations containing 40 mg of telmisartan (n = 30). Right panel: mean (± SE) concentrations over the first 12 hours after administration. The trademarks were Micardis® (Boehringer Ingelheim Promeco, S. A. de C. V, Mexico City, Mexico) for the reference formulation and Raas® (Laboratorios Liomont, S.A. de C.V., Mexico City, Mexico) for the test formulation. |