Table 2

Parameter	Geometric Mean Ratio (%)	90% CI	Probability of Exceeding Limits of Acceptance (lower; upper)		Intra-subject %CV
Telmisartan 40 mg
Cmax	92.32	81.23; 104.94	<0.01	<0.01	29.7
AUC_0-t,	103.39	92.61; 115.41	<0.01	<0.01	25.4
AUC_0-∞	102.79	91.83; 115.05	<0.01	<0.01	24.6

Telmisartan 80 mg
Cmax	102.53	86.84; 121.07	<0.01	<0.01	39.1
AUC_0-t,	99.96	90.51; 110.38	<0.01	<0.01	22.8
AUC_0-∞	100.25	90.58; 110.96	<0.01	<0.01	22.9

AUC_0-t = AUC from time 0 (baseline) to the last measurable concentration
AUC_0-∞ = AUC from baseline extrapolated to infinity
*The limits of acceptance of Cmax (for both studies) are from 75% to 133%, where as the limits of acceptance for both AUC_0-t and AUC_0-∞ are from 80% to 125%.

Table 2: Geometric mean ratios, 90% CIs, the probabilities of exceeding the limits of acceptance and the intra-subject %CV of the pharmacokinetic parameters determined for telmisartan after a single-dose administration of telmisartan (40 mg or 80 mg) in healthy male Mexican subjects.