| Mean age Sex ratio (women/men) Main    clinical manifestations 
              Sensitive polyneuropathy Cognitive disorders Asthenia  Main biological manifestations 
              MacrocytosisAnaemiaLeucopeniaThrombocytopeniaPancytopenia | 76±8 years 2 45% 23% 21% 53% 21% 11% 9% 6.5% |