Cases(%) (n=19) Controls (%) (n=15)
Sex (male:female) 11:8 10:6
Age (median, range) 50.69 (19.0-62.8) 30.37(16.4-65.2)
Type of leukemia
AML
ALL

12(63.2)
7 (36.8)
    
10 (66.7)
5 (33.3)
Chemotherapy in admission in which IMI was diagnosed*^
Induction  
Consolidation
Mobilisation


15 (78.9)
4 (21.1)
0


9 (60.0)
5 (33.3)
1 (6.7)
Duration of neutropenia^
>/=14d
<14d

13 (86.7)
2 (13.3)

1 (6.7)
14 (93.3)
Duration ANC <100/mm3^  
>/=10d
<10d   
15 (78.9)
4 (21.1)
5 (33.3)
10 (66.7)
ANC at diagnosis of leukemia
>/=500/mm3 
<500/mm3 
8 (42.1)
11 (57.9)
13 (86.7)
2(13.3)
Absolute monocyte count #*
<120/mm3 
>120/mm3 
9 (47.4)
10 (52.6)

11 (73.3)
3 (20.0)
No. given FQ prophylaxis   9 (47.4) 9 (60)
No. given ITC prophylaxis 14 (73.7) 12 (80)
No. given syrup ITC 14 (73.7) 14 (93.3)
Anti-fungal prophylaxis >14days 5 (26.3) 8(53.3)
Median LOS (days) 46 (22-88) 23 (9-65)
* for controls, this was the chemotherapy received in the month (± 1 month) in which the IMD in the matched case was diagnosed
^ refers to admission during which IMD was diagnosed
refers to absolute monocyte count on date of diagnosis of IMD, value not available for 1 control
α 5 of the cases did not receive ITC
ANC: Absolute Neutrophil Count; LOS: Length of Stay; FQ: Fluoroquinolone; ITC: Itraconazole
Table 1: Baseline Demographics.