Author
(Year) |
No. of patients |
Maintenance schedule |
PFS or EFS(MR vs. observation) |
OS(MR vs. Observation) |
| Hochster
2009 [14] |
387 |
Four weekly doses every 6 months for 2 years |
64%* vs. 33%
(3 years) |
91% vs. 86%
(3 years) |
| Martinelli 2010 [16] |
202 |
Single dose at 3, 5, 7 and 9 months |
24 months* vs. 13 months |
Difference not statistically significant |
| Salles
2011 [12] |
1217 |
Single dose every 2 months for 2 years |
75%* vs. 58%
(3 years) |
Not significantly different between the two arms |
| Vitolo
2011 [15] |
242 |
Single dose every 2 months for 4 doses |
80% versus 68%
(2 years) |
No data available |
Abbreviations: MR: Maintenance Rituximab; OS: Overall Survival; PFS: Progression
Free Survival