1) Acute lymphoblastic leukemia/lymphoma
Synonyms: Former FAB L1/L2
(a) Precursor B-cell acute lymphoblastic leukemia (cytogenetic subgroups)
• t(12;21)(p13;q22) TEL/AML1
• t(9;22)(q34;q11) BCR/ABL
• t(V;11)(V;q23) V/MLL
• t(1;19)(q23;p13) E2A/PBX1
• Hypodiploid
• Hyperdiploid
(b) Precursor T-cell acute lymphoblastic leukemia
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2) Burkitt cell leukemia/lymphoma
Synonyms: Former FAB L3 |
V: variables [23].
BCR: Breakpoint cluster gene ABL: Abelson gene
AML 1: Acute myeloid leukemia gene 1
MLL: Mixed lineage leukemia gene
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