Figure 4: Time course from the tail-snip tests of hemophilic (FVIIIKO) mice after administrating of: lipid ND - blue, rpFVIII - magenta, rpFVIII bound to ND (rpFVIII-ND) - orange and no treatment (no Tx) in green. The time course is shown as a graph of the surface of the ‘blood spots’ from Figure 3 in arbitrary pixels for each mouse over 20 minutes.