Model Mean standardized difference (95% CI) % changed statistical significance (95% CI)
No adjustment 172.3 (138-207) 51.9 (0.38-0.66)
I) Single linear term 71.69 (51.7-91.7) 15.4 (6.9-28.1)
II) Categories (5) 21.1 (14.3-28.9) 5.8 (1.2-12.1)
IIb) Categories (4) 23.4 (15.6-31.2) 11.5 (4.4-23.4)
IIc) Categories (3) 49.6 (28.1-71.1) 15.4 (6.9-28.1)
IId) Binary variables 48.5 (28.8-68.2) 13.5 (5.6-25.8)
FP 12.7 (10.0-15.4) 3.9 (0.5-13.2)
GAM 0 0
FP: Fractional Polynomials, GAM: smoothing splines in a Generalized Additive
Model
Table 3: Mean standardized difference in parameter estimates, and percent change in statistical significance (p<0.05) compared to the GAM model.