CCAx, BIFx and ICAx PE SE p Corr Model1 Int 0.466 0.038 0.000 0.738 0.091 0.000 -0.180 0.074 0.014 Model2 Int 0.521 0.049 0.000 0.784 0.096 0.000 -0.286 0.095 0.003 dage -0.041 0.018 0.023 dbmi -0.007 0.020 0.723 Corr(CCAx,BIFx) 0.417 0.037 0.000 Corr(CCAx,ICAx) 0.266 0.029 0.000 Corr(BIFx,ICAx) -0.305 0.074 0.000 NOTE: PE: canonical correlation estimate; Others are same with the previous table

Table 8: Heritability estimates for CCAx, BIFx and ICAx using the proposed method: 440 Multiple trait analysis