Method γ Total Loss l1 Penalty SSE SSE Increase Cost Penalty Cost (per patient) Cost Decrease Lasso - 348 17 331 - - - - BLARS 0.1 348 9 317 - 22 1.150 -   0.2 370 10 325 2.5% 35 0.925 19.6%   0.5 384 4 368 15.8% 12 0.125 89.1%   1.0 388 0 388 22.2% 0 0.000 100.0%

Table 7: Components in objective functions for different γ values using BIC as the model selection criterion. The percentage increase or decrease are compared with the first BLARS model (γ=0.1). Lasso model was fitted without considering cost effect, and the total loss has only two components.