| Simulation    Model | 
        κ | 
        Estimate | 
        Bias | 
        MCSE | 
        Mean of SEs | 
        MSE | 
        CP (%) | 
       
      
        | Weibull | 
        0 | 
          | 
        0.004 | 
        0.083 | 
        0.085 | 
        0.007 | 
        95.5 | 
       
      
        |   | 
          | 
          | 
        0.003 | 
        0.089 | 
        0.092 | 
        0.008 | 
        95.3 | 
       
      
        |   | 
          | 
          | 
        0.003 | 
        0.082 | 
        0.081 | 
        0.007 | 
        95.6 | 
       
      
        | Mixed Poisson | 
        1 | 
          | 
        0.013 | 
        0.146 | 
        0.145 | 
        0.021 | 
        95.2 | 
       
      
        |   | 
          | 
          | 
        0.013 | 
        0.149 | 
        0.148 | 
        0.022 | 
        95.1 | 
       
      
        |   | 
          | 
          | 
        0.013 | 
        0.149 | 
        0.148 | 
        0.022 | 
        95.0 | 
       
      
        | Mixed Poisson | 
        2 | 
          | 
        0.027 | 
        0.200 | 
        0.202 | 
        0.041 | 
        95.5 | 
       
      
        |   | 
          | 
          | 
        0.030 | 
        0.202 | 
        0.204 | 
        0.042 | 
        95.6 | 
       
      
        |   | 
          | 
          | 
        0.030 | 
        0.203 | 
        0.206 | 
        0.042 | 
        95.3 | 
       
      
        | Increase+Stable | 
        1/2 | 
          | 
        0.005 | 
        0.110 | 
        0.105 | 
        0.012 | 
        94.6  | 
       
      
        |   | 
          | 
          | 
        0.002 | 
        0.095 | 
        0.096 | 
        0.009 | 
        94.7  | 
       
      
        |   | 
          | 
          | 
        0.002 | 
        0.094 | 
        0.096 | 
        0.009 | 
        94.7  | 
       
      
        | Increase+Stable | 
        1 | 
          | 
        0.007 | 
        0.144 | 
        0.145 | 
        0.021 | 
        94.4  | 
       
      
        |   | 
          | 
          | 
        0.007 | 
        0.138 | 
        0.137 | 
        0.019 | 
        94.8  | 
       
      
        |   | 
          | 
          | 
        0.005 | 
        0.136 | 
        0.138 | 
        0.019 | 
        95.1  | 
       
      
        | Increase+Decrease | 
        1/2 | 
          | 
        0.010 | 
        0.118 | 
        0.117 | 
        0.014 | 
        94.2 | 
       
      
        |   | 
          | 
          | 
        0.010 | 
        0.117 | 
        0.118 | 
        0.014 | 
        94.6 | 
       
      
        |   | 
          | 
          | 
        0.006 | 
        0.108 | 
        0.109 | 
        0.012 | 
        95.3 | 
       
      
        | Increase+Decrease | 
        1 | 
          | 
        0.012 | 
        0.161 | 
        0.160 | 
        0.026 | 
        94.3  | 
       
      
        |   | 
          | 
          | 
        0.013 | 
        0.161 | 
        0.161 | 
        0.026 | 
        94.6  | 
       
      
        |   | 
          | 
          | 
        0.013 | 
        0.156 | 
        0.156 | 
        0.025 | 
        94.6  | 
       
      | 
  
  
    | Abbreviations: NB=Negative binomial; PWNB=Piecewise negative binomial; MCSE=Monte Carlo standard error; SE=Stand error; MSE=Means square error; CP =95% CI coverage probability; κ=Overdispersion parameter | 
  
  
    | Table 3: Comparison of different estimates of the overall relative rate through bias, MCSE, mean of SEs, and MSE of relative rate and 95% CI coverage probability (CP) based on 5,000 Monte Carlo simulations (true relative rate ζ=1.0). |