| Variable |
Treatment |
Relative Rate* |
| Mean |
SE |
95% CI |
p-value |
| Nocturnal Hypoglycemic events |
BBT |
1.62 |
0.22 |
(1.25,2.10) |
<0.001 |
| LM |
1.46 |
0.19 |
(1.13,1.88) |
<0.001 |
| Total Hypoglycemic events |
BBT |
1.51 |
0.12 |
(1.29,1.76) |
<0.001 |
| LM |
1.23 |
0.08 |
(1.08,1.41) |
0.002 |
|
*Relative rate of titration period (0-12 week) versus maintenance period (12-24 week)
Abbreviation: BBT=basal bolus therapy (glargine at bedtime plus mealtime insulin lispro); LM=lispro mix 50/50 (50% insulin lispro protamine suspension and 50% lispro); LS Mean=Least square mean; SE=Standard error; PWNB = Piecewise negative binomial |
| Table 6: The estimated relative rate, SE, 95% CI and p-value for comparison of maintenance period versus titration period for nocturnal and total hypoglycemic events within each treatment group based on PWNB. |
