Threshold value, x No. studies with this threshold Sensitivity Specificity
Summary estimate  95% CI Summary estimate 95% CI
lower  upper lower upper
0.13 1 0.919 0.869 0.951 0.760 0.615 0.862
0.14 2 0.916 0.865 0.949 0.764 0.620 0.865
0.15 5 0.914 0.862 0.947 0.768 0.626 0.868
0.16 3 0.911 0.858 0.946 0.772 0.631 0.870
0.17 3 0.908 0.854 0.944 0.776 0.637 0.873
0.18 3 0.906 0.850 0.942 0.780 0.642 0.875
0.19 4 0.903 0.846 0.940 0.784 0.648 0.878
0.2 6 0.900 0.842 0.938 0.788 0.653 0.880
0.21 3 0.897 0.837 0.936 0.792 0.658 0.883
0.22 1 0.893 0.833 0.934 0.796 0.663 0.885
0.23 1 0.890 0.828 0.932 0.799 0.668 0.887
0.24 2 0.887 0.824 0.929 0.803 0.673 0.890
0.25 2 0.884 0.819 0.927 0.807 0.679 0.892
0.28 2 0.873 0.804 0.920 0.817 0.693 0.898
0.3 4 0.865 0.793 0.915 0.824 0.703 0.903
0.31 1 0.861 0.788 0.912 0.827 0.708 0.905
0.32 1 0.857 0.782 0.909 0.831 0.712 0.907
0.35 1 0.844 0.764 0.901 0.840 0.726 0.912
0.39 2 0.826 0.739 0.888 0.852 0.743 0.920
0.4 2 0.821 0.732 0.885 0.855 0.748 0.922
0.45 1 0.795 0.697 0.868 0.869 0.768 0.930
0.49 1 0.773 0.666 0.853 0.879 0.783 0.936
0.5 2 0.767 0.658 0.849 0.881 0.787 0.937
Table 3: Summary results from REML estimation of meta-analysis model (6) (linear relationship).