| Method |
Arm |
Response rate |
# of patient assigned (SD) |
Pr(selected) |
#of positive response |
degree of imbalance |
Percentage of significantly imbalanced covariate |
| Scenario1: p1=p2=p3=0.1 |
EQ
(τ1=τ2=0) |
A |
0.1 |
30.21 (4.17) |
0.077 |
8.91 |
0.26 |
0.128 |
| B |
0.1 |
29.97 (4.04) |
0.077 |
| C |
0.1 |
29.83 (4.21) |
0.075 |
RA
(τ1=1,τ2=0) |
A |
0.1 |
29.17 (17.51) |
0.053 |
8.92 |
0.25 |
0.127 |
| B |
0.1 |
30.70 (18.01) |
0.054 |
| C |
0.1 |
30.13 (17.97) |
0.061 |
CA
(τ1=0,τ2=1) |
A |
0.1 |
30.11 (4.63) |
0.061 |
8.93 |
0.15 |
0.002 |
| B |
0.1 |
30.12 (4.44) |
0.061 |
| C |
0.1 |
29.77 (4.45) |
0.062 |
| RACA1 |
A |
0.1 |
30.70 (14.61) |
0.068 |
8.95 |
0.19 |
0.023 |
| B |
0.1 |
29.36 (14.08) |
0.062 |
| C |
0.1 |
29.94 (14.24) |
0.067 |
RACA2
(τ1=τ2=1) |
A |
0.1 |
29.70 (11.71) |
0.056 |
9.15 |
0.17 |
0.002 |
| B |
0.1 |
30.35 (11.45) |
0.061 |
| C |
0.1 |
29.95 (11.88) |
0.06 |
RACA3
(τ1=1,τ2=2) |
A |
0.1 |
30.54 (9.05) |
0.053 |
9.1 |
0.16 |
0.002 |
| B |
0.1 |
29.38 (8.82) |
0.053 |
| C |
0.1 |
30.08 (9.08) |
0.058 |
| Scenario2: p1=0.1,p2=0.2,p3=0.3 |
EQ
(τ1=τ2=0) |
A |
0.1 |
30.11 (4.15) |
0.058 |
17.54 |
0.25 |
0.124 |
| B |
0.2 |
30.00 (4.04) |
0.587 |
| C |
0.3 |
29.89 (4.23) |
0.969 |
RA
(τ1=1,τ2=0) |
A |
0.1 |
15.75 (7.84) |
0.048 |
21.28 |
0.23 |
0.114 |
| B |
0.2 |
26.55 (15.98) |
0.422 |
| C |
0.3 |
47.69 (17.18) |
0.856 |
CA
(τ1=0,τ2=1) |
A |
0.1 |
29.84 (4.37) |
0.061 |
17.96 |
0.14 |
0 |
| B |
0.2 |
30.35 (4.47) |
0.59 |
| C |
0.3 |
29.81 (4.57) |
0.949 |
| RACA1 |
A |
0.1 |
16.90 (6.88) |
0.04 |
21.08 |
0.18 |
0.02 |
| B |
0.2 |
26.26 (11.86) |
0.486 |
| C |
0.3 |
46.84 (13.17) |
0.942 |
RACA2
(τ1=τ2=1) |
A |
0.1 |
18.11 (5.68) |
0.047 |
20.87 |
0.16 |
0 |
| B |
0.2 |
27.45 (9.01) |
0.499 |
| C |
0.3 |
44.44 (10.28) |
0.958 |
RACA3
(τ1=1,τ2=2) |
A |
0.1 |
20.61 (5.82) |
0.049 |
20.66 |
0.15 |
0 |
| B |
0.2 |
27.54 (8.19) |
0.53 |
| C |
0.3 |
41.85 (9.48) |
0.964 |
|
