| Repetition |
Mixed Model |
Wilcoxon Signed-Rank Test |
| 1 |
0.041 |
0.139 |
| 2 |
0.043 |
0.138 |
| 3 |
0.049 |
0.137 |
| 4 |
0.044 |
0.136 |
| 5 |
0.045 |
0.135 |
| 6 |
0.040 |
0.135 |
| 7 |
0.041 |
0.134 |
| 8 |
0.044 |
0.143 |
| 9 |
0.043 |
0.134 |
| 10 |
0.054 |
0.138 |
| Overall |
0.044 |
0.137 |
For each repetition, the simulation dataset consisted of 744 gene sets and
P-values for patient specific pathway activities were calculated for each of the 18
patient samples. Therefore the type I error rates were calculated based on a total
of 13392 tests (744 gene sets ×18 patient samples) for each repetition. |
