Product yield (%) FAME yield (%) Factor Coefficient estimated Standard error F-value P-value Coefficient estimated Standard error F-value P-value Intercept 96.02 0.31     97.33 0.37     Linear                 X1 1.12 0.25 19.95 0.0004 1.70 0.30 33.02 <0.0001 X2 1.15 0.25 20.99 0.0003 0.76 0.30 6.62 0.0204 X3 0.44 0.25 3.16 0.0944 1.11 0.30 14.09 0.0017 X4 1.39 0.25 30.87 <0.0001 3.54 0.30 142.94 <0.0001 Quadratic                 X12 -0.86 0.66 1.70 0.2103 -1.05 0.78 1.80 0.1981 X22 -0.08 0.66 0.01 0.9054 0.12 0.78 0.02 0.8769 X32 -0.13 0.66 0.04 0.8466 -0.63 0.78 0.65 0.4336 X42 -1.91 0.66 8.38 0.0105 -2.23 0.78 8.19 0.0113 Interaction                 X1X2 -1.08 0.27 16.63 0.0009 -0.10 0.31 0.11 0.7501 X1X3 -0.68 0.27 6.49 0.0215 0.37 0.31 1.37 0.2595 X1X4 -2.57 0.27 93.76 <0.0001 -1.95 0.31 38.66 < 0.0001 X2X3 -0.88 0.27 11.09 0.0042 -0.26 0.31 0.69 0.4191 X2X4 -1.14 0.27 18.34 0.0006 -0.61 0.31 3.77 0.0701 X3X4 -0.64 0.27 5.76 0.0289 -0.85 0.31 7.28 0.0158

Table 3: The analysis of variance (ANOVA) and estimated regression coefficients for the product yield and the FAME yield models.