Potentialdrug Drug company or sponsor(s) Chemical description Biological processinhibited Current stageof development Bedaquiline Tibotec& TB Alliance Diarylquinolone ATP synthesis Phase II PA-824 TB Alliance Nitroimidazo-oxazine Mycolic acid synthesis Phase II Delamanid OtsukaPharma Nitroimidazo-oxazole Mycolic acid synthesis Phase II SQ109 Sequella Ethylenediamine derivative Cell wall synthesis Phase II Sutezolid Pfizer Oxazolidinone derivative Protein synthesis Phase II AZD5847 Astra-Zeneca Oxazolidinone derivative Protein synthesis Phase I FAS 20013 FASgen Inc. Unknown Lipid/cell wall synthesis Phase I

Table 1: Potential drugs in various phases of development for treatment of drugsusceptible TB and MDR-TB/XDR-TB.