| Virulence factors |
Related genes |
C. diphtheriae NCTC 13129
NC_002935 |
C. efficiens YS-314
NC_004369 |
C. glutamicum R
NC_009342 |
C. jeikeium K411
NC_007164 |
C. pseudotuberculosis FRC41 NC_014329 |
| Adherence |
|
|
|
|
|
|
| Collagen-binding protein |
cbpA |
|
|
|
jk0461 |
|
| SpaA-type pili |
spaA |
DIP2013 |
CE2737, CE2455, CE2457 |
|
|
|
| |
srtA |
DIP2012 |
CE2738 |
|
|
cpfrc_01905 |
| |
spaB |
DIP2011 |
|
|
|
|
| |
spaC |
DIP2010 |
|
|
|
cpfrc_01901, cpfrc_01902, cpfrc_01903 |
| SpaD-type pili |
srtB |
DIP0233 |
|
|
|
cpfrc_01875 |
| |
spaD |
DIP0235 |
|
cgR_2789 |
jk1701 |
cpfrc_01874 |
| |
srtC |
DIP0236 |
|
|
jk1700 |
cpfrc_01873 |
| |
spaE |
DIP0237 |
|
|
jk1699 |
|
| |
spaF |
DIP0238 |
|
|
|
|
| SpaH-type pili |
spaI |
DIP2223 |
|
|
|
cpfrc_01904 |
| |
srtE |
DIP2224 |
|
cgR_2790, cgR_2793 |
|
|
| |
srtD |
DIP2225 |
CE2454, CE2456 |
|
|
|
| |
spaH |
DIP2226 |
|
cgR_2791 |
|
|
| |
spaG |
DIP2227 |
|
|
|
|
| Surface-anchored pilus proteins |
sapA |
DIP2066 |
|
|
jk1702 |
cpfrc_01870 |
| |
sapD |
DIP0443 |
|
|
jk1856 |
|
| |
sapE |
|
|
|
jk0007 |
|
| Iron uptake |
|
|
|
|
|
|
| ABC transporter |
fagC |
DIP1059 |
CE0684 |
cgR_0600 |
jk1774 |
cpfrc_00030 |
| |
fagB |
DIP1060 |
CE0685 |
cgR_0601 |
jk1773 |
cpfrc_00031 |
| |
fagA |
DIP1061 |
CE0686 |
cgR_0602 |
jk1772 |
cpfrc_00032 |
| |
fagD |
DIP1062 |
CE0687 |
cgR_2963 |
jk1776 |
cpfrc_00033 |
| ABC-type heme transporter |
hmuT |
DIP0626 |
|
cgR_0462 |
jk0316 |
cpfrc_00455 |
| |
hmuU |
DIP0627 |
CE0694 |
cgR_0463 |
jk0317 |
cpfrc_00456 |
| |
hmuV |
DIP0628 |
CE0693 |
cgR_0464 |
jk0318 |
cpfrc_00457 |
| ciu iron uptake and siderophore biosynthesis system |
ciuA |
DIP0582 |
|
|
jk1296 |
cpfrc_00987 |
| |
ciuB |
DIP0583 |
|
|
jk1295 |
cpfrc_00988 |
| |
ciuC |
DIP0584 |
|
|
jk1294 |
cpfrc_00989 |
| |
ciuD |
DIP0585 |
|
|
jk1293 |
cpfrc_00990 |
| |
ciuE |
DIP0586 |
|
|
|
cpfrc_00991 |
| Siderophore- depenedent iron uptake system |
irp6A |
DIP0108 |
|
|
jk0561 |
|
| |
irp6B |
DIP0109 |
|
|
jk0560 |
|
| |
irp6C |
DIP0110 |
|
|
jk0559 |
|
| Regulation |
|
|
|
|
|
|
| Diphtheria toxin repressor DtxR |
dtxR |
DIP1414 |
CE1812 |
cgR_1750 |
jk1097 |
cpfrc_01219 |
| Toxin |
|
|
|
|
|
|
| Diphtheria toxin (DT) |
tox |
DIP0222 |
|
|
|
|
| Phospholipase D |
pld |
|
|
|
|
cpfrc_00029 |
