Figure 1: The enclosed graph depicts the biological and filogenetical evolutions of P. vivax, P. malariae, and P. ovale (Group A), compared with the extremely more recent evolution pathway of P. falciparum (group B). P. knowlesi (belonging to group C), is the last Plasmodium species which steadily entered the human pathology, and is related to productive and touristic human activities carried out in the forest regions of Malaysia and Borneo. The image has been taken and modified from some studies published by L. Capasso (quoted at reference [1]), in particular with the adjunct of group C malaria parasite.