Figure 6: Dose-dependent effect of APAP on the 3D liver cell model analyzed using biological measurement techniques. A) Cell viability is determined by LDH assay and B) Metabolic activity is measured by MTT assay after 24 h incubation time with APAP. SEM ± 3-4. *p < 0.05 vs 0 mM APAP and **p < 0.005 vs. 0 mM APAP (untreated 3D liver cell models were set as 100%).