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Figure 3: (A) Schematic of the layer-by-layer build up on a nanowire sensor for the BSA antigen/antibody model system; (B) Cyclic Voltammograms and (C) Nyquist plots of (a) pristine gold nanowire electrode;(b) o-ABA modified electrode; (c) BSA (10 mg/mL) modified electrode; (d) ethanolamine blocked electrode; (e) Antibody BSA binding (10 μg/mL). Solution composition: 1 mMFcCOOH in 10 mM PBS. CV scan rate: 100 mVs−1. EIS frequency range: 0.1 Hz to 100 kHz; E=150 mV and ΔV=5 mV. |