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Figure 6: The JAK/STAT and IFN-γ signaling pathways. The nodes and networks are distributed between the extra- and intercellular regions and the interfaces (not drawn to scale). Red- or green-colored genes are significantly increased or decreased, respectively, at all time points after BA spore exposure, compared to the control cells (a color scale is attached at the bottom right corner). The nodes represent the genes or proteins (see legend for detail), and the solid and dashed arrow-headed lines depict the direct and indirect interactions, respectively. |