| Clinical Feature |
Score |
| ANA or SMA |
|
| ≥ 1:40 |
+1 |
| ≥ 1:80 |
+2 |
| LKM-1 ≥ 1:40 |
+2 |
| SLA positive |
+2 |
| Antibodies absent |
0 |
| Serum globulin or IgG |
|
| Above upper normal limit |
+1 |
| >1.1 upper normal limit |
+2 |
| Normal |
0 |
| Hepatitis viral markers |
|
| Positive |
0 |
| Negative |
+2 |
| Liver histology (evidence of hepatitis is a necessary condition) |
|
| Compatible with AIH |
+1 |
| Typical AIH |
+2 |
| Incompatible with AIH |
0 |
| Interpretation of aggregate scores*: |
|
| Probable AIH |
≥ 6 |
| Definite AIH |
≥ 7 |
*Addition of all antibodies, maximum +2 points.
IgG: Immunoglobulin G; ANA: Anti-nuclear Antibodies; SMA: Smooth Muscle
Antibodies; LKM-1: Type 1 Liver-kidney Microsomal Antibodies; SLA: Soluble Liver
Antigen antibodies |
